Between 1999 and 2016, more than 350,000 Americans died from an opioid overdose.
Overdose deaths are still soar, with increased more than 500 percent since 1999. These figures do not include the countless amount of individuals whose lives have been ruined from these powerful painkillers. For years, physicians averted prescribing opioid-based painkillers like OxyContin, Vicodin, or Percocet for anxiety that individuals could become addicted.
However, in the 1990s, attitudes within the medical community failed a seismic change. Physicians, acknowledging that too many people suffer from untreated pain, even additional pain as the fifth critical wellness sign. Besides checking a person’s temperature, blood pressure, pulse, and respiration rate, doctors began asking patients to rate their pain on a scale of 0 to 10.
A patient who reported a pain level of 6 or higher because of back pain, nerve pain, cancer, or any other ailment has been routinely prescribed one of the many opioid painkillers on the market.
Doctors might have felt they were doing right with their own patients, but their good intentions sowed the seeds from this crisis we are experiencing now.
That is because of the manner opioid-based painkillers work…
From Allergic to Dependence to Addiction
Opioids travel through the bloodstream to the brain, where they connect to proteins (called mu opioid receptors). This triggers a intricate biochemical process which relieves pain.
Over time, the brain becomes accustomed to the existence of opioids and needs higher and higher doses to get the very same effects. This can be known as opioid tolerance.
Tolerance becomes addiction when repeated exposure to escalating doses changes the mind so that it works more or less normally when the drugs are present, and abnormally when they’re not.
And people who become dependent on opioids can’t simply quit taking them. That’s because in addition to relieving pain, these powerful drugs release dopamine, a neurotransmitter present in regions of the brain which regulates feelings of joy.
The overstimulation of this system generates a sense of euphoria and encourages repeated usage of the drug simply for enjoyment. At this point, opioid dependence becomes a habit.
Modified Brains, Ruined Lives
Research conducted in the Addiction Institute at Mount Sinai in New York City indicates that opioid addiction impacts the glutamatergic system in the prefrontal cortex, the portion of the brain that modulates judgment and impulse control.
This harm distorts a person’s decision-making skills, inducing an opioid consumer to get rid of the capability to regulate opioid consumption. He or she, essentially, is unable to stop, unable to simply say no.
Current withdrawal applications that transition addicts to methadone and buprenorphine can cause continuing disturbance into the glutamatergic systemrather than allowing the mind to fully heal. This may explain why some people succeed in stopping opioids for a brief while, only to relapse repeatedly.
A Possible Solution
Evidence continues to mount that cannabis might be the trick to solving the esophageal catastrophe.The National Institute on Drug Abuse now acknowledges that”medical marijuana products could have a role in reducing the use of opioids needed to control anxiety”.
Besides preventing opioid dependency, cannabis has the capacity to help cure those who’ve become hooked. Based on Dr. Yasmin Hurd, director of the Addiction Institute, cannabis has the power to”interrogate and interrogate” the brain at the”cellular level,” curing the glutamatergic system which, as we saw above, is ruined by long-term opioid use.
Unfortunately, cannabis is still listed as a Schedule I controlled substance under US law. This means physicians are discouraged from regretting it (even in states which have legalized it), and insurers will not reimburse patients who use it.
But that is changing, as a result of the efforts of many groups appearing to prosecute medical marijuana.
The Tide is Turning Towards Public Approval and Legalization
Following years of public statements that the chemicals in marijuana had NO health advantages, the FDA approved the first drug comprised of an active ingredient derived from bud to treat rare, severe forms of epilepsy at June 2018.
This was an important win for classes concentrated on medical marijuana in the US. While marijuana remains illegal at the US national level, US states and countries around the planet have taken it upon themselves to fix the uneducated opinion that marijuana is still a public pariah and has no redeeming qualities.
California legalized medical marijuana in 1996. Over 30 states in the usa have legalized medical marijuana, together with others planning to follow the identical route to legalization.
Across the planet, more and more nations have legalized or decriminalized cannabis. There are currently 30 countries which have given the green light to medical cannabis in some power, in addition to a little handful of others that enable medical weed use within very strict guidelines, like in the kind of cannabis-derived pharmaceuticals.
Legalizing marijuana moves cash from your black market to the legal sector.
$32 Billion Global Marijuana Market
Global spending on legal cannabis is forecast to grow 230% to $32 billion in 2020 as compared to $9.5 billion in 2017, based on Arcview Market Research and BDS Analytics. The study jobs a vast majority of that, almost $23.4 billion will come from the United States.
“There are a variety of opportunities in foreign authorities… Germany is a hot one. Other nations in Europe are going medical. Mexico legalized medical cannabis. The world is slowly but surely going that way.”
Since Bloomberg reported”The stigma surrounding the 7.2 billion marijuana industry is evaporating as Americans grow increasingly comfortable with the notion, more states allow medical and recreational use, and pot businesses start generating healthy gains.”
And investors are taking note.
Pot stocks are flourishing as investors race to take part in the”Green Rush”. But you need to understand how to locate those businesses until they burst, separating the blockbusters in the duds. Do your search and find your entrance point where you’re comfortable.